Topics
1. Literature and sequence
databases
Literature search
Search a DNA database
Search a protein sequence database
Bacterial genomes
Human genomes
Model organisms
2. Analyse DNA sequence
Predict genes
Translate DNA sequence
3. Analyse protein sequence
Functional annotation
Protein identification by ...
4. Compare your protein sequence
to other proteins
Homology search in sequence
and structure databases
Multi-sequence alignment
and tree visualization
Multi-sequence alignment databases
Patterns, motifs, domains
5. Get a 3D model
If an experimental structure is available:
Get the coordinates ...
Get secondary structure information ...
If only C(alpha) coordinates are
available:
generate backbone and side chain
coordinates
Structure modelling
Quality check of a structure model
Otherwise: do a secondary structure
prediction
6. Visualize a protein structure
Visualize PDB structure
Browser plug-ins
Visualize ligand interactions
Calculate surface and cavities
7. Analyze protein structure
Search for similar structure
Assign to a protein architecture
Enzyme structures
Ramachandran plot
Side chain interactions
Solvent accessibility
Interactions
8. Analyze protein function
Metabolic databases
Active sites in enzymes
Protein families
9. Other useful sites
Catalogs of databases
Courses
Bioinformatics links
Remote server
Deutsches Patent- und Markenamt
Patent search at US Patent and Trademark Office
Network Protein Sequence Analysis
pI, MW, sequence tag, peptide mass
Software to be downloaded:
Tree-Puzzle: Reconstruction of phylogenetic
TreeView: Visualization of Clustal results
Software to be downloaded:
Download the program DSSP (UNIX)
Structure Prediction Meta-Server
Biotech valiation suite for protein structures
Software to be downloaded:
Software to be downloaded:
Software to be downloaded:
Software to be downloaded:
... by enzyme classification (E.C.)
Atlas of side chain interactions
Protein-protein interaction server
Biochemical Pathways (Boehringer)
U of M Biodegradation database
Directory of P450-containing systems
Overview of Strain Collections
BioCatalog (index to biological software)
Principles of Protein Structure
Structure Prediction Flowchart
News
We organize two conferences in 2012 at our Institute:
Aug. 29-31st 2012:
Protein Engineering for Biocatalysis
Sept. 19-21st 2012:
Biocatalysis in Lipid Modification
Our publication made the cover of Nature Chem. Biol, Nov. 2010:
Author profile:
An author profile about Uwe Bornscheuer has been published in Angew. Chem. Int. Ed.
Flyer available:
English version (pdf)
German version (pdf)
Cluster Partner:
Partner in the 'White Biotechnology' cluster 'Biokatalyse2021' funded by the BMBF.
Contact
Prof. Dr.
Uwe Bornscheuer
Institute of Biochemistry
Dept. of Biotechnology & Enzyme Catalysis
Felix-Hausdorff-Str. 4
D-17487 Greifswald/ Germany
Phone:
+49 (0)3834-86-4367
+49 (0)3834-86-4391 (Secr.)
Fax:
+49 (0)3834-86-794367
E-Mail:
uwe.bornscheuer
